CPAP Cleaning: Weekly & Monthly Checklist

How to clean your CPAP machine, mask, tubing and humidifier — a weekly and monthly routine to keep your therapy safe and effective.

Written By
AHCEQUIP Team
Published on
June 30, 2026
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A clean CPAP setup isn't just about hygiene — it directly affects how well your therapy works. Buildup in the mask, tubing, or humidifier chamber can reduce airflow and introduce bacteria you're breathing in all night. Here's a simple weekly and monthly routine.

Daily

  • Empty and air-dry the water chamber if you don't refill it fresh each night.
  • Wipe down the mask cushion with a damp cloth if visibly soiled.

Weekly

  • Mask: Wash the cushion and frame in warm water with mild soap (avoid harsh detergents or alcohol-based cleaners), rinse thoroughly, and air-dry.
  • Tubing: Wash with warm soapy water, rinse, and hang to air-dry completely before reconnecting.
  • Headgear: Hand-wash and air-dry; avoid the washing machine unless the manufacturer specifically allows it.

Monthly

  • Water chamber: Deep clean with a vinegar-water soak (check your manufacturer's guidance) to remove mineral buildup, then rinse thoroughly.
  • Filters: Replace disposable filters; rinse and inspect non-disposable (foam) filters for damage.
  • Machine exterior: Wipe down with a damp cloth, keeping moisture away from the air intake and electrical components.

What Not to Do

Avoid ozone cleaners and UV sanitizing devices not approved by your CPAP manufacturer — the FDA has warned these can be ineffective or even damage equipment. Stick to manufacturer-recommended soap and water cleaning.

When to Replace, Not Just Clean

Cleaning extends the life of your supplies, but parts still wear out on a schedule. See our CPAP resupply schedule guide for when insurance covers new masks, tubing, and filters.

Frequently Asked Questions

Can I put my CPAP mask in the dishwasher?

No — hand-washing with mild soap and warm water is recommended to avoid damaging the silicone seal and frame.

How often should I replace the water in my humidifier chamber?

Use fresh distilled water nightly, and empty any unused water each morning rather than letting it sit.

Are CPAP cleaning machines (ozone/UV) safe to use?

The FDA advises against unapproved ozone and UV cleaning devices. Manufacturer-recommended soap-and-water cleaning remains the safest method.

How do I know if my tubing needs replacing instead of just cleaning?

Look for cracks, stiffness, or persistent odor after cleaning — these indicate it's time to replace rather than continue cleaning.

For official guidance on CPAP cleaning devices, see the FDA's consumer safety resources. Questions about your CPAP setup? Contact AHCEQUIP — we're here to help.

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